Current Members:
Allen B. Reitz, Ph.D.; PDDI President, Chairman of the Board, and Founding Member: Dr. Reitz is CEO of the Fox Chase Chemical Diversity Center, Inc. (FCCDC), and ALS Biopharma, LLC. He has three decades of experience in the area of medicinal chemistry, including 26 years with Johnson & Johnson. He led the medicinal chemistry efforts in the area of diseases of the central nervous system for 16 years at the J&J facility in Spring House, PA, which accounted for the introduction of seven new drug candidates into human clinical evaluation. He has 60 issued U.S. patents and 140 scientific publications. In addition, Dr. Reitz is the Founding Editor of the jouirnals Current Topics in Medicinal Chemistry (www.bentham.org/ctmc) and Technology Transfer and Entrepreneurship. He is experienced in the area of translational drug discovery as a scientist and entrepreneur. [link to LinkedIn page]
Dennis M. Gross, M.S., Ph.D.; PDDI Chief Executive Officer and Secretary/Treasurer: Dr.
Gross is also
Adjunct Faculty in the
Jefferson Graduate School of Biomedical Sciences and the Sidney Kimmel Medical
School of Thomas Jefferson University and adjunct Professor of Basic Sciences at the Geisinger Commonwealth School of Medicine. He received B.A and M.S.
degrees in biology from California State University, Northridge and a
Ph.D. in cell biology from UCLA; he conducted postdoctoral studies at
Tulane University School of Medicine. Dr. Gross joined Merck Sharp &
Dohme Research Labs in 1977 and held several positions of increasing
responsibility in his 29-year career: bench scientist, head of computer
resources, manager of international strategic planning, and liaison for
research and clinical drug development in Japan. As Senior Director for
Business Operations and Planning, he was responsible for global,
multisite operations at Merck. He has served as Adjunct Professor of
Global Logistics in the School of Business and Industry of Florida
A&M University and has worked with the Center for Strategic and
International Studies on policy issues relating to biological WMD. From 2006 until July 2014, Dr.
Gross has served as Associate Dean and Director, College of Graduate Studies at Thomas Jefferson University and Associate Professor of Pharmacology and Experimental Therapeutics in Jefferson Medical College. [link to LinkedIn page]
Rodney A. Bednar, Ph.D.; PDDI Vice President, Chair of Philadelphia Chapter of LRIG: Dr. Bednar is a drug discovery scientist and industry leader in the biochemistry and automation of lead optimization assays. The LRIG
is an organization with over 12,000 members worldwide, principally from
biopharma, with an interest in lab automation and data management.
Until recently, he was a Director at the Merck Research Laboratories,
where he was recognized with a Special Achievement Award for providing
leadership in the use of fragment-based screening in more than 30
discovery programs. Dr. Bednar is an adjunct faculty at SUNY-Stony
Brook, where he holds joint appointments as Assistant Professor of
Pharmacological Sciences in the Medical School and Assistant Professor
of Chemistry in the School of Arts and Sciences. He received his Ph.D.
in chemistry and biochemistry from the University of Delaware and did
postdoc training in biochemistry and physical organic chemistry at
Brandeis University. He has 52 refereed publications, 38 abstracts, and
over 23 invited talks. [link to LinkedIn page]
Bruce E. Maryanoff, Ph.D.; PDDI Professor of Chemical Biology and Chair of Scientific Advisory Board: Dr. Maryanoff is also Foundation Distinguished Professor of the Institute for Hepatitis and Virus Research; Investigator, The Scripps Research Institute-La Jolla; and Associate Editor, ACS Medicinal Chemistry Letters. He retired from Johnson & Johnson after 36 years of service in the field of medicinal
chemistry, having led drug discovery research mainly in central nervous system and cardiovascular areas. This activity resulted in 23 compounds entering preclinical development, 13 of which advanced to human clinical studies. Dr. Maryanoff discovered TOPAMAX (topiramate), a billion-dollar drug that is useful for the treatment of epilepsy and migraine. He
has published 275 scientific papers and is an inventor on 100 U.S.
patents (issued or pending); has received three American Chemical Society (ACS) national awards and
the 2009 Edward E. Smissman Award; and was inducted into the ACS Division of Medicinal Chemistry
Hall of Fame in 2008. He was elected Fellow in the ACS (inaugural class), American Association for the Advancement of Science, and the Royal Society of Chemistry. [link to LinkedIn page]
Joseph
F. Aceto, Ph.D, Esq., Attorney at Law and Counsel at Obermayer Rebmann Maxwell
and Hippel: Dr. Aceto graduated from Temple University
with a Ph.D. in pharmacology and from Widener University with a J.D. in law. He is a registered Intellectual
Property attorney and is admitted to practice in Pennsylvania and before the U.S.
Patent and Trademark Office. His private
practice involves primarily patent prosecution and licensing, working
extensively with biotech and pharmaceutical
companies, universities, and non-profit research institutions. He has worked with individual inventors,
partnerships, and companies in securing patent protection and establishing a portfolio
around new pharmaceuticals, medical devices, and diagnostics. Dr. Aceto is also Of Counsel at
Obermayer Rebmann Maxwell and Hippel, where he assists companies in establishing
and securing copyright and trademark protection. [link to LinkedIn page]
Paul S. Anderson, Ph.D., Senior Vice President, DuPont-Merck (ret.):
Dr. Anderson received a B.S. in chemistry from the University of Vermont in 1959 and a Ph.D. in chemistry
from the University of New Hampshire in 1963. After postdoctoral work at Cornell University, he joined
Merck Sharp & Dohme Research Laboratories where he rose through the ranks to
become Vice President for Chemistry at West Point, PA. In 1994, he retired from Merck to become the Senior Vice
President for Chemical and Physical Sciences at the DuPont-Merck Pharmaceuticals
Company (later DuPont Pharmaceuticals Company). In 1997 Dr. Anderson served as
President of the American Chemical Society (ACS). He received the E. B. Herschberg Award for important
discoveries in medicinally-active substances from the ACS
in 1995. He received a Doctor of
Science Honoris Causa from the University of Vermont and a Doctor of
Chemistry Honoris Causa from the University of New Hampshire. Dr. Anderson was recipient of the
ACS Award in Industrial Chemistry in 2001, the Perkin
Medal in 2002 and the National Academy of Sciences Award for Chemistry in
Service to Society in 2003. In
2006, the ACS recognized Dr. Anderson with its highest
honor, the Priestley Medal. [link to LinkedIn page]
Ned D. Heindel, Ph.D., Howard S. Bunn
Chair Professor, Lehigh University: Dr. Heindel received a B.S. in chemistry at Lebanon
Valley College in 1959 and a Ph.D. from the University of Delaware in
1963. After an NSF Postdoctoral
Fellowship at Princeton University, he joined the faculties of Marshall
University and Ohio University. In 1966 he relocated to Lehigh University where
his research has involved the development of diagnostic and therapeutic
products. Dr. Heindel has consulted in big and small pharma, and has mentored
41 doctoral students, 147 M.S. students, and 27 postdoctoral fellows, most of
whom have undertaken careers inside the pharmaceutical industry. He has served on 2 corporate boards, 5
scientific advisory boards, 3 editorial boards, 4 professional boards, and 2
government commissions. He directs the medicinal chemistry research program of Azevan
Pharmaceuticals and the drug development program for Project CounterACT-Rutgers,
a federal program seeking antidotes for sulfur mustard poisoning. In 1994 Dr. Heindel served as President
of the American Chemical Society (ACS).
He holds 11 patents and has published 282 papers. He received the NOBCChE-Henry Hill Award in medicinal chemistry, the
Brady Foundation award for research in tumor-imaging radiopharmaceuticals, and
the Hillman award for educational and research achievements. In 2009 he was named
a Fellow of the ACS. [link to LinkedIn page]
Marlene A. Jacobson, Associate Professor of Pharmacodynamics and Associate Director of the Moulder Center for Drug Discovery Research, Temple University School of Pharmacy:
Dr. Jacobson received a bachelor degree in chemistry from Douglass College, Rutgers University, and a Ph.D. in chemistry from the University of Delaware. She was awarded a NIH Post-Doctoral Fellowship at
MIT with a secondary appointment as Visiting Fellow in Genetics at Harvard Medical
School. In 1987, Dr. Jacobson joined Merck Research Laboratories, where she pursued drug
discovery and preclinical development in areas of neuroscience, including
schizophrenia, Alzheimer’s disease, and sleep disorders. Dr. Jacobson is
recognized for her contributions to the discovery and development of allosteric
modulators of G-protein-coupled receptors, including muscarinic and metabotropic
glutamate receptors. In
2012, she joined the faculty of Temple University's School of Pharmacy. Her current research
interests include identification of treatments for neuropathic lysosomal
storage disorders, and novel screening methods and assay development for
drug discovery.
Gregory F. Krug, President, Lampire Biological Laboratories, Inc.:
Mr. Krug, founder of Lampire Biological Laboratories, has guided the company’s growth and development since its inception in 1977. He completed acquisition of the corporation in 1979 and holds 100% ownership; he is responsible for the operation and financial performance of the company. As Chief Executive officer, Mr. Krug has the ultimate responsibility for compliance with all federal, state, and local regulatory agencies. As Institutional Official, Mr. Krug appoints the Institutional Animal Care and Use Committee (IACUC) to review, investigate and report all activities related to Animal Welfare in compliance with 9 CFR Chapter (Code of Federal Regulation). He is active in professional associations and highly involved in the local community. Mr. Krug received the Achievement Award in Animal Science for his accomplishments in the field from Delaware Valley College Alumni Association, the 2005 Entrepreneur Award by Pennsylvania Business Central, and 2006 Pennsylvania Small Business Exporter of the Year Award by the Small Business Administration. [link to LinkedIn page]
Dr. James K. Murray, Jr. – Professor of
Organic Chemistry, Department of Natural & Computational Sciences, Immaculata
University
Dr. Jim Murray
received his B.S. (1996) in Chemistry and his M.S. (1997) and Ph.D. (2003) in
Organic Chemistry from Drexel
University. During his undergraduate studies he worked as
an analytical chemist analyzing polymer modifiers at Rohm & Haas
Corporation and as an organic chemist in the medicinal chemistry department of
GlaxoSmithKline. Dr. Murray has over 25 years’
experience in organic synthesis, product isolation/purification, and nuclear
magnetic resonance (NMR) spectroscopic analysis. He has been on the faculty of Immaculata
University since the fall of 2001 teaching courses in organic, medicinal, physical,
and inorganic chemistry. Dr. Murray’s
research interests cover the areas of organic chemistry, organic chemistry
education, and medicinal chemistry education.
He is interested in developing experiments that introduce new
methodologies and techniques that can be used as effective teaching tools and
to developing methods to introduce medicinal chemistry concepts into the
undergraduate organic chemistry curriculum. Dr. Murray is a past officer of the
Philadelphia Organic Chemists’ Club (POCC), 2019 Chair of the Philadelphia
Section of the American Chemical Society (ACS), and a member of the ACS
Divisions of Organic Chemistry, Medicinal Chemistry, and Chemical Education.
Alumni:
Kathleen M. Czupich, MBA; Assistant Treasurer and Founding Member:
Ms. Czupich has over 20 years experience in business development and
was the founding administrator for the IHVR and the PA Biotech Center.
Ms. Czupich managed the financial and administrative aspects of the $7.9
million grant to construct the PA Biotech Center (PBC) and the
resulting building project totaling more than $14 million. She
was also instrumental in the negotiation, financing and purchase of the
adjacent building, expanding the PBC to 115,000 square feet. Ms. Czupich
works on business development, grants administration, and the management of early-stage technology-based businesses. She is the CFO for FCCDC. where she has managed a portfolio involving >$8 million in federal grant funding. [link to LinkedIn page]
Ceile E. Hedberg, DVM, Ph.D., Senior Director of Alliance Management, Johnson & Johnson Pharmaceutical Sector (ret.): Dr.
Hedberg
received her D.V.M. from the School of
Veterinary Medicine of Tuskegee University and her Ph.D. in anatomy and
structural biology from the University of Pennsylvania. After
postdoctoral
training in the Department of Psychology at Princeton University, she
became the
manager of lab animal resources at Rutgers University in Piscataway, NJ,
then manager of lab animal resources at Carter-Wallace. She
held several positions of increasing responsibility at the R.W. Johnson
Pharmaceutical Research Institute, including Director of Lab Animal
Medicine. She
moved to the Johnson & Johnson Pharmaceutical
Services to work on global trademark development and served as Senior
Director for Alliance Management and Business
Development in Janssen Global Services. She is a member of a number of
boards of
directors including the Pennsylvania Society for Biomedical Research,
Scientists Center for Animal Welfare, and the Advisory Board for Bennett
College. [link to LinkedIn page]
Donna M. Huryn, Ph.D., Professor of Chemistry, University of Pennsylvania: Dr. Huryn graduated with a Ph.D. in organic chemistry from the University of Pennsylvania. She spent 20 years in the pharmaceutical industry, at both Hoffmann-La Roche and Wyeth Research, where she directed the Neuroscience Medicinal Chemistry Department as well as the Chemical Sciences Interface Department. In 2004 she joined academia with an appointment at the University of Pittsburgh School of Pharmacy. She is now on the faculty of the University of Pennsylvania, Department of Chemistry. [link to LinkedIn page]
Dennis C. Liotta, Ph.D., Professor of Chemistry, Emory University: Dr. Liotta has extensive experience in multidisciplinary research and his laboratory is noted for its collaborative efforts that span a rich spectrum of academic departments. Over the past two and a half decades Dr. Liotta's research has focused on the discovery and development of novel antiviral, anticancer and antiinflammatory therapeutic agents. He is one of the leaders of the Emory team that developed the antiviral drug, FTC (Emtriva), which was approved for HIV in July 2003. In addition, he is the inventor of record for several clinically important antivirals, including 3TC (Epivir, lamivudine), D-D4FC (Reverset, DPC-817), Racivir (racemic FTC) and L-D4FC (elvucitabine). He is also the lead inventor of MSX-122, a safe, orally available clinical agent for treating cancer and inflammation. [link to LinkedIn page]